ShapeME: A tool and web front-end for de novo discovery of structural motifs underpinning protein-DNA interactions
Jeremy W. Schroeder, Vivian Ramirez, Michael B. Wolfe, Lydia Freddolino
ShapeME discovers structural DNA motifs that improve prediction of protein-DNA binding beyond traditional PWMs using ChIP-seq data.
Journal of Molecular Biology · Apr 15, 2026Peer-reviewedBioinformatics