Author

Xiafei Zhang

McMaster University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Organism:C. elegans· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Approach:statistical model· 1

Frequent Co-Authors

Marie A. ElliotiD· 2 shared Biel Badia Roigé· 1 shared Dagmara JakimowicziD· 1 shared Doris Dohmen-Olma· 1 shared Hindra Hindra· 1 shared Johanna WiechertiD· 1 shared Julia FrunzkeiD· 1 shared Lauren Tiller· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Marie A. ElliotORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

LsrL modulates Lsr2-induced chromatin structure to tune biosynthetic gene cluster regulation in Streptomyces venezuelae

Vivian Ramirez, Lauren Tiller, Marcin Jan Szafran, Xiafei Zhang, Dagmara Jakimowicz, Marie A. Elliot, Lydia Freddolino

This study investigates how Lsr2 and LsrL regulate chromatin structure and biosynthetic gene clusters in Streptomyces venezuelae using multi-omics approaches.

bioRxiv · Nov 23, 2025 · PreprintMicrobiology

CRISPR/dCas-mediated counter-silencing: Reprogramming dCas proteins into antagonists of xenogeneic silencers

Johanna Wiechert, Biel Badia Roigé, Doris Dohmen-Olma, Hindra Hindra, Xiafei Zhang, Roberto G. Stella, Marie A. Elliot, Julia Frunzke

This paper introduces CRISPRcosi, a CRISPR/dCas-mediated method to counteract xenogeneic silencers in actinobacteria, achieving gene activation without promoter engineering.

mBio · May 28, 2025Peer-reviewedMicrobiology