Biologically-informed machine learning identifies a new clinically-actionable bladder cancer subgroup characterised by NRF2 overactivity
Vlad V. Ungureanu, Richard T. Gawne, Simon C. Baker, Pontus Eriksson, David M. Halliday, Stephen L. Smith, Jennifer Southgate, Andrew S. Mason
The paper uses biologically-informed machine learning to identify a new bladder cancer subgroup with NRF2 overactivity, which is clinically actionable and resistant to standard treatments.
bioRxiv · Jun 3, 2025 · PreprintCancer Biology