Mechanical instabilities of aorta drive blood stem cell production: a live study
Nausicaa Poullet, Ivan Golushko, Vladimir Lorman, Jana Trávníčková, Charlotte Bureau, Dmitrii V. Chalin, S. B. Rochal, Andrea Parmeggiani, Karima Kissa
The paper shows that mechanical instabilities in the aorta drive the extrusion of haematopoietic stem/progenitor cells during embryogenesis through collective endothelial cell migration.
Cellular and Molecular Life Sciences · Nov 15, 2019Peer-reviewedDevelopmental Biology