Author

Vladimir Vinogradov

University of Toronto

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Systems Biology· 1

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Approach:statistical model· 1

Frequent Co-Authors

Eduardo D. SontagiD· 1 shared Harsh Vardhan JainiD· 1 shared Irina KarevaiD· 1 shared Jana L. GevertziD· 1 shared Joel S. BrowniD· 1 shared Kathleen P. WilkieiD· 1 shared Mark Davies· 1 shared Yitong HuangiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperSystems Biology

Eduardo D. SontagORCID

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1 paper

Recent·Most cited

Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedJan 7, 2026

Delaying Cancer Progression by Integrating Toxicity Constraints in a Model of Adaptive Therapy

Jana L. Gevertz, Harsh Vardhan Jain, Irina Kareva…·Mark Davies

This paper develops a mathematical model to assess how incorporating toxicity feedback affects adaptive cancer therapy, finding that toxicity-induced treatment breaks can extend time to progression.

3 citationstop 2%

statistical model

𝕏 PostBluesky