Cancer BiologybioRxiv
A cross-species drug discovery pipeline to identify and validate new treatments for osteosarcoma
J. Somarelli, G. Rupprecht, E. Altunel…·D. Hsu
This study develops a cross-species drug discovery pipeline to identify and validate new treatments for osteosarcoma, finding that dual inhibition of proteasome and CRM1 pathways induces synergistic cytotoxicity.
DOI 10.3390/cancers12113335