Processing of oxidatively damaged DNA dirty ends by APE1
A. M. Whitaker, W. J. Stark, B. D. Freudenthal
This study characterizes APE1's exo activity on 3-8-oxoG substrates, revealing a unified mechanism distinct from its AP-endonuclease activity and identifying unique protein:DNA contacts for 8-oxoG removal.
bioRxiv · Nov 28, 2021 · PreprintBiochemistry