W. Karlen

Physiologically driven, altitude-adaptive model for the interpretation of pediatric oxygen saturation at altitudes above 2000 m a.s.l.

The paper develops a physiology-based model to predict and interpret pediatric oxygen saturation at high altitudes, showing it better identifies normal ranges than statistical thresholds.

A transformation of oxygen saturation (the saturation virtual shunt) to improve clinical prediction model calibration and interpretation

The paper introduces a transformation of SpO2 called saturation gap to improve clinical prediction model calibration and interpretation by providing a linearly interpretable measure of disease severity.