Utilization of a Histoplasma capsulatum zinc reporter reveals the complexities of fungal sensing of metal deprivation
L. T. Blancett, H. M. Evans, K. Candor, W. R. Buesing, J. L. Figueroa, G. S. Deepe
This paper constructs a ZRT2 zinc importer reporter in Histoplasma capsulatum to study metal sensing during infection, showing ZRT2 upregulation in GM-CSF-stimulated macrophages and its role in fungal pathogenesis.
bioRxiv · Nov 14, 2023 · PreprintMicrobiology