Machine Learning Elucidates Design Features of Plasmid DNA Lipid Nanoparticles for Cell Type-Preferential Transfection
L. Cheng, Y. Zhu, J. Ma, A. Aggarwal, W. H. Toh, C. Shin, W. Sangpachatanaruk, G. Weng, R. Kumar, H.-Q. Mao
This study uses machine learning to identify LNP composition parameters that enhance transfection efficiency across cell types and modulate cell type-preferentiality.
bioRxiv · Dec 7, 2023 · PreprintBioengineering