NeuroscienceJournal of NeurosciencePeer-reviewed
Radiogenomics of C9orf72 expansion carriers reveals global transposable element de-repression and enables prediction of thalamic atrophy and clinical impairment
Luke W. Bonham, Ethan G. Geier, Daniel W. Sirkis…·Jennifer S. Yokoyama
The paper investigates C9orf72 expansion carriers using radiogenomics to link peripheral blood transcriptomics with thalamic atrophy and clinical impairment, finding global transposable element de-repression and associations between C9orf72 expression and disease severity.
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