SPRI: Structure-Based Pathogenicity Relationship Identifier for Predicting Effects of Single Missense Variants and Discovery of Higher-Order Cancer Susceptibility Clusters of Mutations
Boshen Wang, Xue Lei, Wei Tian, Alan Perez-Rathke, Yan Yuan Tseng, Jie Liang
SPRI predicts the pathogenicity of missense variants and identifies spatially organized mutational clusters linked to cancer and Mendelian diseases.
Briefings in Bioinformatics · Jun 8, 2023Peer-reviewedBioinformatics