De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments
Kevin Eloff, Konstantinos Kalogeropoulos, Amandla Mabona, Oliver Morell, Rachel Catzel, Esperanza Rivera‐de‐Torre, Jakob Berg Jespersen, Wesley Williams, Sam P. B. van Beljouw, Marcin J. Skwark, Andreas H. Laustsen, Stan J. J. Brouns, Anne Ljungars, Erwin M. Schoof, Jeroen Van Goey, , Timothy P. Jenkins
InstaNovo is a transformer model for de novo peptide sequencing that outperforms existing methods, enabling accurate identification of peptides and discovery of novel sequences and organisms.
Nature Machine Intelligence · Mar 31, 2025Peer-reviewedBioinformatics