Author

Xiang Shao

Shanghai Jiao Tong University

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Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:protein design· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Cheng ZhuiD· 1 shared Chengyun ZhangiD· 1 shared Hongliang DuaniD· 1 shared Huitian LiniD· 1 shared Kang Lin· 1 shared Ning Zhu· 1 shared Tianfeng ShangiD· 1 shared Xudong Wang· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBioinformatics

Cheng ZhuORCID

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1 paper

Recent·Most cited

HighPlay：Cyclic Peptide Sequence Design Based on Reinforcement Learning and Protein Structure Prediction

Huitian Lin, Cheng Zhu, Tianfeng Shang, Ning Zhu, Kang Lin, Chengyun Zhang, Xiang Shao, Xudong Wang, Hongliang Duan

HighPlay uses reinforcement learning and protein structure prediction to design cyclic peptides with good binding affinity, validated through molecular dynamics simulation and experimental testing.

Journal of Medicinal Chemistry · May 23, 2025Peer-reviewedBioinformatics