BioinformaticsJournal of Medicinal ChemistryPeer-reviewed
HighPlay:Cyclic Peptide Sequence Design Based on Reinforcement Learning and Protein Structure Prediction
Huitian Lin, Cheng Zhu, Tianfeng Shang…·Hongliang Duan
HighPlay uses reinforcement learning and protein structure prediction to design cyclic peptides with good binding affinity, validated through molecular dynamics simulation and experimental testing.
10 citations