Whole-Genome Promoter Profiling of Plasma Cell-Free DNA Exhibits Predictive Value for Preterm Birth
Zhiwei Guo, Ke Wang, Xiang Huang, Kun Li, Guojun Ouyang, Xu Yang, Jiayu Tan, Haihong Shi, Liangping Luo, Xincai Zhang, Min Zhang, Bo‐Wei Han, Xiang-Ming Zhai, Yingsong Wu, Fang Yang, , Jia Tang
The paper develops a classifier, PTerm, using whole-genome promoter profiling of plasma cell-free DNA to predict preterm birth with high accuracy across multiple validation cohorts.
medRxiv · Sep 20, 2022 · PreprintGenetic & Genomic Medicine