CellPolaris: Decoding Cell Fate through Generalization Transfer Learning of Gene Regulatory Networks
Guihai Feng, Xin Qin, Jiahao Zhang, Wuliang Huang, Yiyang Zhang, Wentao Cui, Shirui Li, Chen Yao, Wenhao Liu, Yao Tian, Yana Liu, Jingxi Dong, Ping Xu, Zhenpeng Man, Guole Liu, , Xin Li
CellPolaris uses transfer learning to generate cell-type-specific gene regulatory networks from transcriptomic data, achieving state-of-the-art results in predicting regulatory factors and simulating cell fate transitions.
bioRxiv · Sep 25, 2023 · PreprintBioinformatics