Author

Jingxi Dong

Chinese Academy of SciencesORCID 0009-0001-2017-584XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Guihai FengiD· 3 shared Guole LiuiD· 3 shared Yana LiuiD· 3 shared Yuanchun ZhouiD· 3 shared Chengrui WangiD· 2 shared Ge YangiD· 2 shared Hongmei WangiD· 2 shared Jiahao ZhangiD· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Guihai FengORCID

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Author profile →

3 papers

Recent·Most cited

scCompass: An integrated cross-species scRNA-seq database for AI-ready

Pengfei Wang, Wenhao Liu, Jiajia Wang, Yana Liu, Pengjiang Li, Ping Xu, Wentao Cui, Ran Zhang, Qingqing Long, Zhilong Hu, Fang Chen, Jingxi Dong, Chunyang Zhang, Yan Chen, Chengrui Wang, , Yuanchun Zhou

scCompass provides a cross-species scRNA-seq database with standardized preprocessing, enabling AI-ready data for research and analysis.

bioRxiv · Nov 12, 2024 · PreprintBioinformatics

GeneCompass: Deciphering Universal Gene Regulatory Mechanisms with Knowledge-Informed Cross-Species Foundation Model

Xiaodong Yang, Guole Liu, Guihai Feng, Dechao Bu, Pengfei Wang, Jie Jiang, Shubai Chen, Qinmeng Yang, Hefan Miao, Yiyang Zhang, Zhenpeng Man, Zhongming Liang, Zichen Wang, Yaning Li, Zheng Li, , Zeyuan Zhang

GeneCompass is a cross-species foundation model pre-trained on single-cell transcriptomes from human and mouse, integrating biological knowledge to improve gene regulatory mechanism understanding and downstream tasks.

Cell Research · Oct 7, 2024Peer-reviewedBioinformatics

CellPolaris: Decoding Cell Fate through Generalization Transfer Learning of Gene Regulatory Networks

Guihai Feng, Xin Qin, Jiahao Zhang, Wuliang Huang, Yiyang Zhang, Wentao Cui, Shirui Li, Chen Yao, Wenhao Liu, Yao Tian, Yana Liu, Jingxi Dong, Ping Xu, Zhenpeng Man, Guole Liu, , Xin Li

CellPolaris uses transfer learning to generate cell-type-specific gene regulatory networks from transcriptomic data, achieving state-of-the-art results in predicting regulatory factors and simulating cell fate transitions.

bioRxiv · Sep 25, 2023 · PreprintBioinformatics