TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits
Sini Nagpal, Xiaoran Meng, Michael P. Epstein, Lam C. Tsoi, Matthew T. Patrick, Greg C. Gibson, Philip L. De Jager, David Alan Bennett, Aliza P. Wingo, Thomas S. Wingo, Jingjing Yang
The paper introduces a Bayesian method for transcriptomic data imputation that improves gene mapping of complex traits by enhancing imputation accuracy and TWAS power over existing tools.
The American Journal of Human Genetics · Jun 20, 2019Peer-reviewedGenetics