iCNG99: a validated genome-scale metabolic model of Cryptococcus neoformans strain H99
Chun Feng, Pengjie Hu, Yin Zhu, Weixin Ke, Xindi Gao, Chen Ding, Bing Zhai, Linqi Wang, Ziwei Dai
The paper develops and validates a genome-scale metabolic model for Cryptococcus neoformans strain H99, showing high precision in essential gene prediction and capturing metabolic adaptations relevant to drug tolerance and host survival.
bioRxiv · Apr 15, 2026 · PreprintSystems Biology