Direct Conversion Of Human Fibroblasts Into Osteoblasts And Osteocytes With Small Molecules And A Single Factor, Runx2
Yanjiao Li, YaoLong Wang, Juehua Yu, Zhaoxia Ma, Qiong Bai, Xingfei Wu, Pengfei Bao, Lirong Li, Daiping Ma, Jinxue Liu, Change Liu, Fangyun Chen, Min Hu
This study converts human fibroblasts into osteoblast-like and osteocyte-like cells using Runx2 and small molecules, showing mineralization and bone formation in vivo.
bioRxiv · Apr 14, 2017 · PreprintCell Biology