Cross-ancestry genome-wide association study and systems-level integrative analyses implicate new risk genes and therapeutic targets for depression
Yifan Li, Xinglun Dang, Rui Chen, Zhaowei Teng, Junyang Wang, S. L. Li, Yingying Yue, Brittany L. Mitchell, Yong Zeng, Yong‐Gang Yao, Ming Li, Zhongchun Liu, Yonggui Yuan, Tao Li, Zhijun Zhang, Xiong‐Jian Luo
This study identifies 287 depression risk loci, 140 new, through cross-ancestry GWAS and integrates functional and pathway analyses to highlight potential therapeutic targets.
Nature Human Behaviour · Feb 24, 2025Peer-reviewedGenetic & Genomic Medicine