Multi-stage physics-informed neural networks for JAK--STAT5 signaling and ultradian insulin--glucose dynamics: latent-species identifiability and suppression of parameter-induced divergence
Jie Deng, Xuchang Zhang, Xinyu Zhang, Xing Lin Yang
This paper introduces a multi-stage physics-informed neural network to solve multi-species biochemical dynamics, demonstrating latent-species identifiability and suppression of parameter-induced divergence using synthetic data.
bioRxiv · Jun 17, 2026 · PreprintBiochemistry