Xinyu Zhang

Generalizable sex differences in functional brain organization follow the cortical hierarchy in youth

The paper examines sex differences in functional brain connectivity across youth, finding that males show greater network integration while females show greater network segregation along the sensorimotor-association axis.

Detecting domain-level organization in genome-wide association study summary statistics using frequency-impact-reliability profiles

This paper introduces FIR-GWAS, a framework that reveals domain-level organization in GWAS summary statistics by analyzing frequency-impact-reliability profiles across multiple traits and species.

Multi-stage physics-informed neural networks for JAK--STAT5 signaling and ultradian insulin--glucose dynamics: latent-species identifiability and suppression of parameter-induced divergence

This paper introduces a multi-stage physics-informed neural network to solve multi-species biochemical dynamics, demonstrating latent-species identifiability and suppression of parameter-induced divergence using synthetic data.

Clinical Metabolomics studies in diagnosing Prediabetes and Type 2 Diabetes: Unveiling Trends through Bibliometric Analysis

This study uses bibliometric analysis to identify trends in metabolomics research related to prediabetes and type 2 diabetes, highlighting key topics and influential journals.

Thioredoxin-1 inhibits granulosa cell ferroptosis to rescue ovarian aging through mitophagy-dependent activation of BNIP3L

This study shows that Thioredoxin-1 prevents granulosa cell ferroptosis by promoting mitophagy, thereby improving ovarian aging and fertility in mice.

5-Hydroxymethylcytosines from Circulating Cell-free DNA as Diagnostic and Prognostic Markers for Hepatocellular Carcinoma

This study develops a 5-hydroxymethylcytosine (5hmC) diagnostic model from circulating cell-free DNA to detect hepatocellular carcinoma with high accuracy and prognostic value.