Sequence- and structure-selective mRNA m5C methylation by NSUN6 in animals
Jianheng Fox Liu, Tao Huang, Yusen Zhang, Tianxuan Zhao, Xueni Zhao, Wanying Chen, Rui Zhang
The paper identifies NSUN6 as an mRNA methyltransferase targeting Type II m5C sites and reveals its structural specificity and functional relationship with translation efficiency.
National Science Review · Oct 29, 2020Peer-reviewedMolecular Biology