ImmunologybioRxivPreprint
Immune gene co-expression networks are constrained by a non-linear topology spectral relationship
Roberto Navarro Quiroz, Eloina Zarate Peñate, Lisandro Pacheco-Lugo…·Elkin Navarro Quiroz
The paper analyzes immune gene co-expression networks across two cohorts and finds that neither modularity nor spectral dominance alone distinguishes healthy from disease states, but their joint distribution reveals a geometric constraint.
DOI 10.64898/2025.12.25.696503