Kidney pathology alters cell-clustering in single cell RNA sequencing
L. Ma, M. Murea, Y. A. Choi, A. K. Hemal, A. V. Mikhailov, J. A. Snipes, J. W. Chou, R. C. Langefeld, W. Cui, L. D. Miller, G. A. Hawkins, N. D. Palmer, C. D. Langefeld, B. I. Freedman
The paper shows that kidney injury affects cell clustering in scRNA-Seq by reducing specific cell groups and markers, emphasizing the need for histology screening before analysis.
bioRxiv · Oct 8, 2021Cell Biology