Identification of antigen-specific TCR sequences using a strategy based on biological and statistical enrichment in unselected subjects
N. P. Smith, B. Ruiter, Y. V. Virkud, W. G. Shreffler
The paper develops a method combining biological and statistical enrichment to identify antigen-specific TCR sequences in unselected subjects, finding 36 public CDR3 sequences with high convergent recombination.
bioRxiv · May 11, 2020Immunology