Author

N. P. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

A.-C. Villani· 2 shared K. Manakongtreecheep· 2 shared A. L. Kley· 1 shared A. Lawless· 1 shared A. Tirard· 1 shared B. Ruiter· 1 shared B. Y. Arnold· 1 shared C. J. Pinto· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

A.-C. Villani

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Author profile →

3 papers

Recent·Most cited

Resident memory T cell development is associated with AP-1 transcription factor upregulation across anatomical niches.

N. P. Smith, Y. Yan, Y. Pan, J. B. Williams, K. Manakongtreecheep, S. Pant, J. Zhao, T. Tian, T. Pan, C. Stingley, K. Wu, J. Zhang, A. L. Kley, P. K. Sorger, A.-C. Villani, T. S. Kupper

This study identifies AP-1 transcription factors as key regulators of TRM development across tissues using scRNA-seq and ATAC-seq, revealing a novel mechanism for TRM reactivation.

bioRxiv · Sep 29, 2023 · PreprintImmunology

Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor

S. M. Blum, D. A. Zlotoff, N. P. Smith, I. J. Kernin, S. Ramesh, L. Zubiri, J. Caplin, N. Samanta, S. C. Martin, A. Tirard, P. Sen, Y. Song, J. L. Barth, K. Slowikowski, M. Nasrallah, , A.-C. Villani

This study identifies immune cell types and biomarkers in irMyocarditis using single-cell RNA sequencing and TCR analysis across heart, blood, and tumor tissues.

bioRxiv · Sep 15, 2023 · PreprintImmunology

Identification of antigen-specific TCR sequences using a strategy based on biological and statistical enrichment in unselected subjects

N. P. Smith, B. Ruiter, Y. V. Virkud, W. G. Shreffler

The paper develops a method combining biological and statistical enrichment to identify antigen-specific TCR sequences in unselected subjects, finding 36 public CDR3 sequences with high convergent recombination.

bioRxiv · May 11, 2020Immunology