SARS-CoV-2 Spike Protein Reduces Burst Activities in Neurons Measured by Micro-Electrode Arrays
M. Salvador, N. Tseng, C. Park, G. Williams, A. Vethan, G. Thomas, J. Baker, J. Hemry, E. Hammond, P. Freeburg, G.-W. Chou, N. Taylor, Y.-F. Lu
This study shows that SARS-CoV-2 S1 protein reduces neuronal burst activity in vitro, while S2 does not, and this effect is blocked by an anti-S1 antibody.
bioRxiv · Apr 24, 2023Microbiology