A CSF Proteomic Clock Reveals Opposing Brain-Aging Programs and Predicts Neurological Disease Progression
Shenrui Xu, Yangying Guo, Ke Fang, Suli Li, Tingting Wang, Y L Li, Mengyi Zhang, Hongyan Li, Tao Xu, Zhichao Miao, Yining Yang, Zonghong Li
The paper develops a CSF proteomic aging clock that predicts age and disease progression, identifying opposing aging programs associated with neurological disorders.
bioRxiv · Jul 1, 2026 · PreprintNeuroscience