Microglia from Friedreich Ataxia patients are intrinsically primed for neuroinflammation
Ye Man Tang, Rita Lo, Louise Thiry, Michael R. Fiorini, Sali Farhan, Massimo Pandolfo, Stefano Stifani
This study shows that microglia from Friedreich Ataxia patients have an intrinsic pro-inflammatory phenotype due to FXN deficiency, identifying potential therapeutic targets.
bioRxiv · Jul 21, 2026 · PreprintNeuroscience