Executive control in Obsessive-Compulsive Disorder: A worldwide mega-analysis of task-based functional neuroimaging data of the ENIGMA-OCD consortium
Nadža Džinalija, Ilya Milos Veer, Helen Blair Simpson, Iliyan Ivanov, Srinivas Balachander, Francesco Benedetti, Federico Calesella, Sophie Fitzsimmons, Rosa Grützmann, Kristen Hagen, Bjarne K. A. Hansen, Stephan Heinzel, Chaim Huyser, Jonathan Ipser, Fern Jaspers‐Fayer, , Chris Vriend
This study analyzes fMRI data from OCD patients and controls to identify neural activation patterns during executive control tasks, finding reduced activation in frontoparietal regions and increased default mode network activity in OCD.
bioRxiv · Aug 20, 2025 · PreprintNeuroscience