Blood-spinal cord barrier leakage is independent of motor neuron pathology in ALS
Sarah Waters, Birger Victor Dieriks, Molly E. V. Swanson, Yibin Zhang, Natasha Lillia Grimsey, Helen C. Murray, Clinton P. Turner, Henry John Waldvogel, Richard L. M. Faull, Jiyan An, Robert P. Bowser, Maurice A. Curtis, Mike Dragunow, Emma L. Scotter
The paper examines whether blood-spinal cord barrier breakdown correlates with motor neuron loss and TDP-43 proteinopathy in ALS, finding they have distinct regional patterns.
Acta Neuropathologica Communications · Aug 26, 2021Peer-reviewedNeuroscience