A human forebrain organoid model reveals the essential function of GTF2IRD1-TTR-ERK axis for the neurodevelopmental deficits of Williams Syndrome
Xingsen Zhao, Qihang Sun, Yikai Shou, Weijun Chen, Mengxuan Wang, Wenzheng Qu, Xiaoli Huang, Ying Li, Chao Wang, Yan Gu, Chai Ji, Qiang Shu, Xuekun Li
This study uses human forebrain organoids to show that the GTF2IRD1-TTR-ERK pathway is critical for neurodevelopmental deficits in Williams Syndrome.
eLife · Dec 13, 2024Peer-reviewedNeuroscience