Macrophages employ quorum licensing to regulate collective activation
Joseph J. Muldoon, Yishan Chuang, Neda Bagheri, Joshua N. Leonard
The paper shows macrophages use quorum licensing, a density-dependent mechanism, to regulate collective activation in response to LPS, leading to bimodal phenotypic partitioning.
Nature Communications · Feb 13, 2020Peer-reviewedSystems Biology