Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea Subtype
Pavithra Nagarajan, Nuzulul Kurniansyah, Jiwon Lee, Sina A. Gharib, Yushan Xu, Yiyan Zhang, Brian Spitzer, Tariq O. Faquih, Hufeng Zhou, Eric Boerwinkle, Han Chen, Daniel J. Gottlieb, Xiuqing Guo, Nancy L. Heard‐Costa, Bertha Hidalgo, , Heming Wang
This study identifies gene-environment interactions between excessive daytime sleepiness and genetic variants linked to obstructive sleep apnea severity, revealing novel therapeutic targets.
medRxiv · Oct 25, 2024 · PreprintGenetic & Genomic Medicine