Author

Pavithra Nagarajan

Brigham and Women's HospitalORCID 0000-0002-0036-9970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:statistical model· 6 Assay:GWAS summary statistics· 5 Research Focus:GWAS / association mapping· 4 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Tariq O. FaquihiD· 6 shared Brian E. CadeiD· 5 shared Xiuqing GuoiD· 5 shared Aldi T. Kraja· 4 shared Amy R. BentleyiD· 4 shared C. Charles GuiD· 4 shared Jingxian Tang· 4 shared Karen SchwanderiD· 4 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersGenetic & Genomic Medicine

Tariq O. FaquihORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Gene-by-Sleep Duration Interaction for Glycemic Traits in over 480,000 Individuals

H. Wang, Pavithra Nagarajan, Clint L. Miller, Amy R. Bentley, Raymond Noordam, Kenneth E. Westerman, Michael F. Brown, Aldi T. Kraja, Jeffrey R. O’Connell, Karen Schwander, Changwei Li, Mihir M. Sanghvi, Yipei Song, Traci M. Bartz, Vincent Braunack-Mayer, , Caroline Hayward

The paper identifies 16 genetic loci interacting with sleep duration to influence glycemic traits in over 480,000 individuals, revealing distinct biological mechanisms for short and long sleep.

Diabetes · Oct 29, 2026Peer-reviewedGenetic & Genomic Medicine

Large-Scale Gene-Smoking Interactions and Fine Mapping Study Identifies Multiple Novel Blood Pressure Loci in over 1 Million Individuals

Mengyu Zhang, Michael R. Brown, Amy R. Bentley, Thomas W. Winkler, Raymond Noordam, Pavithra Nagarajan, Bohong Guo, Songmi Lee, Karen Schwander, Wenyi Wang, Kenneth E. Westerman, Jeffrey R. O’Connell, Farah Ammous, Anna D. Argoty-Pantoja, Traci M. Bartz, , Bertha Hidalgo

This study identifies twelve novel blood pressure loci and shows smoking modifies genetic effects on BP through immune-related pathways in over 1 million individuals.

medRxiv · Oct 6, 2025 · PreprintGenetic & Genomic Medicine

A Large-Scale Genome-Wide Study of Gene-Sleep Duration Interactions for Blood Pressure in 811,405 Individuals from Diverse Populations

Pavithra Nagarajan, Thomas W. Winkler, Amy R. Bentley, Clint L. Miller, Aldi T. Kraja, Karen Schwander, Songmi Lee, Wenyi Wang, Michael R. Brown, John L. Morrison, Ayush Giri, Jeffrey R. O’Connell, Traci M. Bartz, Lisa de las Fuentes, Valborg Guðmundsdóttir, , Stephen S. Rich

This study identifies 22 novel gene-sleep duration interaction loci for blood pressure traits across 811,405 individuals, highlighting distinct genetic influences of short and long sleep on cardiovascular health.

Molecular Psychiatry · Apr 4, 2025Peer-reviewedGenetic & Genomic Medicine

Genome-wide association analysis of composite sleep health scores in 413,904 individuals

Matthew O. Goodman, Tariq O. Faquih, Valentina Paz, Pavithra Nagarajan, Jacqueline M. Lane, Brian Spitzer, Matthew Maher, Joon Chung, Brian E. Cade, Shaun Purcell, Xiaofeng Zhu, Raymond Noordam, Andrew J. K. Phillips, Simon David Kyle, Kai Spiegelhalder, , Heming Wang

This study performs genome-wide association analysis on composite sleep health scores, identifying 28 novel loci and confirming 341 previously reported loci, with insights into genetic mechanisms and pathways.

Communications Biology · Jan 24, 2025Peer-reviewedGenetic & Genomic Medicine

Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea Subtype

Pavithra Nagarajan, Nuzulul Kurniansyah, Jiwon Lee, Sina A. Gharib, Yushan Xu, Yiyan Zhang, Brian Spitzer, Tariq O. Faquih, Hufeng Zhou, Eric Boerwinkle, Han Chen, Daniel J. Gottlieb, Xiuqing Guo, Nancy L. Heard‐Costa, Bertha Hidalgo, , Heming Wang

This study identifies gene-environment interactions between excessive daytime sleepiness and genetic variants linked to obstructive sleep apnea severity, revealing novel therapeutic targets.

medRxiv · Oct 25, 2024 · PreprintGenetic & Genomic Medicine

A Large-Scale Genome-Wide Gene-Sleep Interaction Study in 732,564 Participants Identifies Lipid Loci Explaining Sleep-Associated Lipid Disturbances

Raymond Noordam, Wenyi Wang, Pavithra Nagarajan, Heming Wang, Michael R Brown, Amy R. Bentley, Qin Hui, Aldi T. Kraja, John L. Morrison, Jeffrey R. O’Connel, Songmi Lee, Karen Schwander, Traci M. Bartz, Lisa de las Fuentes, Mary Furlan Feitosa, , Rima Destya Triatin

This study identifies 17 genetic loci associated with sleep duration and lipid levels, offering potential druggable targets for dyslipidemia in individuals with sleep disturbances.

medRxiv · Sep 2, 2024 · PreprintGenetic & Genomic Medicine