Author

Yoolim A. Choi

Columbia University Irving Medical Center

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Bioinformatics· 1

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Approach:Bayesian inference· 1 Assay:scRNA-seq· 1 Research Focus:variant effect prediction· 1

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Guojie ZhongiD· 1 shared Yufeng SheniD· 1 shared

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2022-2022 · peak 1/yr

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Guojie ZhongORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintMay 13, 2022

Integration of single cell gene expression data in Bayesian association analysis of rare variants

Guojie Zhong, Yoolim A. Choi, Yufeng Shen

VBASS integrates single-cell expression and de novo variant data to enhance power in discovering disease risk genes, showing better performance than existing methods on simulated data and identifying more candidate risk genes.

DOI 10.1101/2022.05.13.491893

scRNA-seqBayesian inference

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