The Analgesic and Dissociative Properties of Ketamine are Separate and Correspond to Distinct Neural Mechanisms
Noam Goldway, Talma Hendler, Itamar Jalon, Yotam Pasternak, Roy Sar-El, Dan Mirelman, Noam Sarna, Nili Green, Yara Agbaria, Haggai Sharon
This study investigates whether ketamine's analgesic and dissociative effects are mediated by distinct neural mechanisms and finds they are independent.
bioRxiv · Jul 25, 2025 · PreprintNeuroscience