Spatial Transcriptomics Reveals a Conserved Border Niche and Etiology-Associated Immune Rewiring in Hepatocellular Carcinoma
Sungwoo Bae, Heesun Choi, Su Young Hong, YoungRok Choi, Kwang Woong Lee, Kwon Joong Na, Suk Kyun Hong
This study uses spatial transcriptomics to compare the tumor-stroma border in HBV-related and NBNC HCC, identifying conserved desmoplastic niches and etiology-specific immune signaling differences.
bioRxiv · Jun 5, 2026 · PreprintCancer Biology