Heesun Choi

This paper introduces STRATA, a framework that models interactions between lipid nanoparticle components and their ratios to improve prediction of transfection efficiency.

This study uses spatial transcriptomics to compare the tumor-stroma border in HBV-related and NBNC HCC, identifying conserved desmoplastic niches and etiology-specific immune signaling differences.

This study identifies spatial tumor microenvironment features of chemoradiotherapy-resistant residual esophageal squamous cell carcinoma using spatial transcriptomics and single-cell analysis, revealing SPP1-associated macrophage programs and microvascular rarefaction as key factors.

The paper identifies multi-loop chromatin miswiring in FAD-mutant neurons that correlates with gene expression changes and DLX transcription factor activity.