Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival
Jongkyun Kang, Guodong Huang, Long Ma, Youren Tong, Anu Shahapal, Phoenix Chen, Jie Shen
This study shows that LRRK1 and LRRK2 are essential for dopaminergic neuron survival, as their deletion leads to age-dependent neurodegeneration in mice.
eLife · Jun 10, 2024Peer-reviewedNeuroscience