Bottom-up engineering of EV-mimetic vesicles reveals selective protein loading and modulates cellular uptake and biodistribution
Yunxi Chen, Yousra Benslimane, Noélie Douanne, Kyle Dickinson, Thupten Tsering, Masoud Ghasemi, Laura Kienzle, Elisabet Frutos-Grilo, David Juncker, Anne‐Laure Larroque, Luis G. Serrano, Vahé Nerguizian, Julia Valdemarin Burnier
The paper engineers EV-mimetic vesicles to study protein loading and uptake, finding that protein properties influence incorporation and biodistribution.
bioRxiv · Oct 6, 2026 · PreprintBioengineering