Ultrasensitive detection of neuronal DNA using genome-wide non-CG methylation patterns
Netanel Loyfer, Amit Horn, Shmuel Hart, Jonathan Rosenski, Sheina Piyanzin, Judith Magenheim, Ofra Sabag, Adi Avniel Aran, Yshia Langer, Natalie Barsoum, Guy Rosenthal, Moshe Gat, Kim Olthoff, Abraham Shaked, Ruth Shemer, , Yuval Dor
This paper detects neuronal DNA in cfDNA using non-CpG methylation patterns, finding elevated levels in neurological conditions and brain-dead donors.
bioRxiv · Nov 2, 2026 · PreprintGenomics