Author

Sheina Piyanzin

Hebrew University of Jerusalem

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Assay:DNA methylation· 4 Organism:human· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Ruth ShemeriD· 4 shared Yuval DoriD· 4 shared Benjamin GläseriD· 3 shared Judith MagenheimiD· 3 shared Netanel LoyferiD· 3 shared Tommy KaplaniD· 3 shared Amit Horn· 2 shared Ayelet PeretziD· 2 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenomics

Ruth ShemerORCID

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Author profile →

4 papers

Recent·Most cited

Ultrasensitive detection of neuronal DNA using genome-wide non-CG methylation patterns

Netanel Loyfer, Amit Horn, Shmuel Hart, Jonathan Rosenski, Sheina Piyanzin, Judith Magenheim, Ofra Sabag, Adi Avniel Aran, Yshia Langer, Natalie Barsoum, Guy Rosenthal, Moshe Gat, Kim Olthoff, Abraham Shaked, Ruth Shemer, , Yuval Dor

This paper detects neuronal DNA in cfDNA using non-CpG methylation patterns, finding elevated levels in neurological conditions and brain-dead donors.

bioRxiv · Nov 2, 2026 · PreprintGenomics

Time is encoded by methylation changes at clustered CpG sites

Bracha-Lea Ochana, Daniel Nudelman, Daniel Cohen, Ayelet Peretz, Sheina Piyanzin, Ofer Gal-Rosenberg, Amit Horn, Netanel Loyfer, Miri Varshavsky, Ron Raisch, Ilona Shapiro, Yechiel Friedlander, Hagit Hochner, Benjamin Gläser, Yuval Dor, , Ruth Shemer

The paper shows that DNA methylation changes at clustered CpG sites encode chronological age with high accuracy using deep learning on blood samples.

Cell Reports · Jul 1, 2025Peer-reviewedGenomics

Remote immune processes revealed by immune-derived circulating cell-free DNA

Ilana Fox-Fisher, Sheina Piyanzin, Bracha-Lea Ochana, Agnes Klochendler, Judith Magenheim, Ayelet Peretz, Netanel Loyfer, Joshua Moss, Daniel Cohen, Yaron Drori, Nehemya Friedman, Michal Mandelboim, Marc E. Rothenberg, Julie M. Caldwell, Mark Rochman, , Yuval Dor

The paper uses immune cell type-specific methylation patterns in circulating cell-free DNA to monitor immune dynamics and find that immune-derived cfDNA levels reflect immune homeostasis and predict immune responses to perturbations.

eLife · Nov 26, 2021Peer-reviewedGenomics

Specific detection of cell-free DNA derived from intestinal epithelial cells using methylation patterns

Roni Lehmann‐Werman, Aviad Zick, Cloud Peter Paweletz, Marisa W. Welch, Ayala Hubert, Miriam Maoz, Tal Davidy, Judith Magenheim, Sheina Piyanzin, Daniel Neiman, Joshua Moss, Hadar Golan, Eran Israeli, Matan Fischer, Eran Segal, , Yuval Dor

The paper identifies methylation patterns specific to intestinal epithelial cells to detect cell-free DNA in plasma, showing increased levels in advanced CRC compared to IBD and PDAC.

bioRxiv · Sep 5, 2018 · PreprintDevelopmental Biology