The Metabolic Role of MAP3K15: Genetic and Phenotypic Insights from the 23andMe Research Database and Genetics-Driven Recruitment
Brady Jennifer J, Kira Kalkus, Dominique T. Nguyen, Jingran Wen, Zachary L. Fuller, Yue Qi, Shaeloren S. Deering, Leah Selcer, Suyash Shringarpure, Michael Vaclav Holmes, Xin Wang
The paper uses the 23andMe database to study MAP3K15's metabolic role, finding LoF carriers have delayed T2D diagnosis and reduced cholesterol.
medRxiv · Jan 9, 2024 · PreprintGenetic & Genomic Medicine