Improved recombinant protein production and scale-up fermentation of Aspergillus oryzae hyphal-dispersion hydrophobin-deficient strain
Shunya Susukida, Yasuhiro Baba, Makoto Fujisawa, Yuki Niikawa, Kiyoaki Muto, Ken Miyazawa, Akira Yoshimi, Yoshikazu Kato, Hirofumi Horiguchi, Keietsu Abe
This study develops a hyphal-dispersion mutant of Aspergillus oryzae with reduced hyphal adhesion and improved enzyme production and bioreactor performance.
bioRxiv · Aug 6, 2026 · PreprintBioengineering