Differentiation independent neuroprotective role of Vcan+ oligodendrocyte precursor cells in poststroke cognitive impairment recovery
Shang-Hang Shen, Yongjie Wang, Ruixue Xia, Fanning Zeng, Jun Cao, Xiaolei Liu, Yunbin Zhang, Zhanxiang Wang, Tao Tao
The paper identifies Vcan+ oligodendrocyte precursor cells as a key cluster in post-stroke cognitive impairment and suggests their neuroprotective role through Vwf signaling from Lcn2+ endothelial cells.
bioRxiv · Nov 7, 2020 · PreprintNeuroscience