Xiaolei Liu

This study shows that IVA337 reduces secondary lymphedema in mice by inhibiting the TGFβ/SMAD2/3 pathway, improving lymphatic function and preventing fibrosis.

This study identifies CXCL12/CXCR4 signaling as critical for lymphatic valve formation through flow-dependent AKT/FOXO1/FOXC2 activation, offering potential therapeutic strategies for lymphedema.

The paper identifies Vcan+ oligodendrocyte precursor cells as a key cluster in post-stroke cognitive impairment and suggests their neuroprotective role through Vwf signaling from Lcn2+ endothelial cells.